No articles match
Matching a differential expression signature to perturbation references using perturbMatch2 months ago
Installation | Background | Overview | Reference signatures | How it works | Preparing input data | Load reference expression data | Choosing a full reference database | Map the query to the reference | Starting from a table or CSV file | Calculating regulator scores | Checking a known target | Using an explicit gene set | Visualise the results | Inspecting a single reference signature | Where the perturbed gene ranks: target_gene_percentile | Filtering on the target percentile | Functional enrichment of the regulator hits | Scoring methods available | Comparing scoring methods | Interpreting the score, zscore, and overlap columns | Tuning topN | Parallelisation | Verifying hits before interpretation | Saving results to a file | Related packages | Citation | Session information | Acknowledgements
perturbMatch reference signatures via ExperimentHub3 months ago
Introduction | Installation | Available datasets | Discovering the data on ExperimentHub | Loading a dataset | Exploring the data | Data provenance | Citing the data | Session info
Matching a single-cell RNA-seq response to perturbation references using perturbMatch3 months ago
Overview | Load the data | Select a cell population | Aggregate into pseudobulk samples | Differential expression | Score candidate regulators | Filtering hits that cannot be human regulators | Visualise the results | Cell-level scoring with singscore | Session information
SkeletalVis: Exploration and Visualisation of Skeletal Transcriptomics Data1 years ago
Getting started | Installation | Loading the package | Accessing the SkeletalVis dataset | Exploring SkeletalVis | Searching all datasets for a gene of interest | Find a dataset of interest | Retrieve a dataset of interest | Filtering a dataset of interest | Volcano plots | Finding similar datasets | Plotting the similarities | Visualising OATargets data